Quaker House is the venue of a series of meetings helping government representatives prepare for the Second Special Session on Disarmament, 1982. A Quaker representative addresses the Special Session.

In partnership with other Quaker service organizations, QUNO facilitates governmental and grassroots civil society initiatives in preparation for the UN World Conference Against Racism, Racial Discrimination, Xenophobia and Related Intolerance.

QUNO facilitated the adoption of the Ministerial Declaration on TRIPs and Public Health at the World Trade Organization (WTO).

Growing out of the work on Women in Prison, QUNO's work on Children of Prisoners begins.

QUNO has been working to make the international intellectual property and trading systems more equitable since the early 1990s. Within its long-standing concern for a fair global economic system, we decided in 2009 to focus our attention on food and sustainability.

Throughout 2010 and 2011, QUNO conducted quiet diplomacy with the UN and in Burundi in order to support civil society participation and perspectives in peacebuilding processes including the UN Peacebuilding Commission.

QUNO New York in collaboration with the American Friends Service Committee hosted a delegation visit of six Chinese academics to Burundi and the Democratic Republic of Congo. The visit provided an opportunity for the delegation members to gain a deeper understanding of UN peacebuilding and prevention efforts on the ground.

In June 2011, QUNO New York worked with other partner organisations to publish a public statement in response to fighting that had erupted in northern Myanmar. The statement included recommendations for immediate action by the Government of Myanmar and the Kachin Independence Army, as well as supportive measures to be taken by China, the Association of Southeast Asian Nations (ASEAN), and the UN.